I have for years. David and I keep trading new ideas for gear. Mostly we just like going to lunch together.
I rigged an Aero-Ektar to a 4x5 SLR Graflex, since I didn't want to copy David's Speed Graphic. It can't focus to infinity (may be out to 6 or 7 feet tops) but it's great for portraiture.
http://www.walterpcalahan.com/Cheers...mm)_f_2.5.html
My web site has various examples of funky camera use on editorial assignments.