I have used a lot of it, and use Hypam fixer. As long as you are careful while handling it, you shouldn't have any problems.
If you use a wipe or squeegee, use it only on the film base side, not the emulsion. I learned that one the hard way.
"Often moments come looking for us". - Robert Frank
"Make good art!" - Neil Gaiman
"...the heart and mind are the true lens of the camera". - Yousuf Karsh