I'm sure you're referring to the Harley and other 45 degree single crankpin twins. A proper v-twin, such as the 90 degree Ducati (aptly named) has very good mechanical balance, abeit masked by the lopsided power strokes.
On the 4x5 Linhof and the Rollei, there isn't enough clearance between the cable release socket and the lensboard to screw in the slave piston assembly.
In the 60's or so a pneumatic tube release kit was on the market which got a short cable intermediary to be installed between the pneumatic cylinder and the shutter.
The problem with all these kits is that the rubber bulbs have disintegrated by now...