22 kilo's? It is often said that when backpacking you should be able to carry 1/3 your own weight so it sounds like a good backpack is just thing you need. Also don't try and get there in one step: when going uphill maintain your pace but shorten your steps. I've been backpacking for over 20yrs and have learned that the best thing you can do is don't be in a hurry. Also unless you workout regularly(aerobic/cardio) you are suddenly asking your body to carry 44 extra lbs which doesn't sound like much but your body knows the difference.