For the Hasselblad V Series, there is no autofocus capability. I believe that there maybe for the H Series.
I have used autofocus with the Nikon cameras and that works well except for cases
when the contrast in the focus area is too low for the electronics to work well or I hope that helps.
when there is something between you and what you want to focus on. Example, when you want to focus on an animal at the zoo in cage the autofocus may want to focus on the cage bars rather than the animal. Or when shooting a store front window and you want to focus on the store interior and the camera wants to focus on the reflections on the window.