Input from a scrawny female with small palms and long fingers:
I don't notice either Nikon or Canon being unwieldy at all. Then again, I shoot my Bronica a-plenty, have used Hasseys with no problem, and am gradually training myself to use my Speed Graphic without a tripod. I have no issues with cameras being too large for my hands, but do sometimes have to get used to the weight of bigger-than-average cams. I'm getting some great arm and shoulder muscles from the Graphic.
If I had to carry a pink camera, I'd go back to painting.