I also have a 16x12 quad, I've had no problems processing FB papers. Usually I use one clip even for 11x14, but I use two occasionally with papers that are very limp when wet. Blighty's suggestion of tongs would work too, and I may try that (thanks!).
Single weight papers might be a problem, but those have mostly disappeared anyway.
The slots on the quad are vertical, with angled slots you may want to process face up so that the back is against the side of the slot, otherwise, no worries I'd think.