I've used Xtol 1+1, xtol 1+2, PMK, and pyrocat HD. I think PMK does the nicest job at highlight detail with TMY2 film; I couldn't get good results out of PMK with fomapan 100 though; probably needs more work on my part. Xtol is good stuff; sort of neutral /all purpose in handling of tones. Pyrocat HD seems to produce a little more snap/bold contrast than xtol for me with TMY2, but doesn't mess up the contrast the same way increasing the paper grade would do. Perhaps it's because it requires less exposure than PMK?.... I haven't done much with pyrocat HD and fomapan100 yet though.
I mostly use MF and LF and TMY2, so grain isnt much of a problem with any developer. I did shoot an indoor concert with 35mm TMY2 in PMK and it was excellent; as stage lights are usually blowing out highlights madly. Good highlights, not much grain to my surprise. I shoot so little 35mm, I haven't tried pyrocat HD in it yet. Xtol is an excellent developer for most 35mm needs.