erkg beat me to it !
... scan 2x or more the resolution you want your final to be
so when you fix / dust &C it won't be evident ...
... save it at a lower resolution + the size you want it saved for your publication
its like skng and saving things for the gallery here,
you wouldn't skn anything at 6x8 @ 72dpi ... dust &c
but you would skn it at 300 or 600 so you can remove the dust &C
and when you shrink it down to 72dpi your "fixes" are not visible ...
have fun !