Well, you know what large-format photographers say about composing on ground glass: if the composition seems to aesthetically work upside-down, then it will work rightside up too. Of course if you're shooting square format like 6x6, you suddenly have four orientation choices instead of two. The composition should work any of four ways. So why not print and display your images completely randomly? By all means flip a coin (or two) to let the prevailing artistic spirits decide.
If a viewer gets puzzled by the results, simply turn up your nose, declaim with righteous indignation that they obviously know nothing about true art, and move on to someone more appreciative.