Yes, theoretically it should vignette or at least show some light falloff but then again I always burn the sides and edges on all my prints so I figured it won't be a big deal. But other then that, I don't know! I'll have to try. But I'm still interested to know other people's experiences. I admit to being a snob when it comes to using my 100mm Focotar-2 but this time I really need to go bigger then 12x12...