Yes. I'm assuming you are using a lens with a shutter, and not a Petzval? Calculate how much light you need. Say all you can get with one pop is f22, but you want f45. Simply cock the shutter, pop the shot, cock the shutter & wait for the strobe to recycle, pop again (f32,) repeat pop again, and again (f45.) Remember that you must double the amount of light to gain a stop. Thus, going from f11 to f22 requires 2 pops for f16 and x2 again for f22--total of four pops, not three.
Kent in SD