Now, there is another issue, the scanner itself, there are plenty of flat bed 1200DPIx16bit scanners out there that will scan at 4800DPIx32bits, they don't actually do this, they scan at 1200DPIx16bits, then use extrapolating software to get the resolution you asked for and do some bit shifting to get 32bit values. I don't know enough about the mechanics of drum scanners to know how much of this they do.
Really though, there is no perfect scan, there is a perfect scan for what you want to do with the image. I never start with a scan, I start with the negative, then set the scanner to get as close to what I want as I can get, resolution is part of that. Scanning should be considered the first step of the printing process, not the last step of negative processing.