The misconception that 35mm cameras have more Depth Of Field than large format has been repeated so often that it is rarely disputed. However, in any format with equal angular coverage and image viewing distance, the DOF is determined only by the entrance pupil. For example, a 50mm lens at f/2 has identical DOF as a 8" lens at f/8. The small format does have an advantage in a faster shutter speed for DOF equal to the larger camera. The larger grain in 35mm cameras may also mask its DOF limitations. A large view camera has swings and tilts that give it the advantage of focus plane adjustment that are available only with expensive tilt and shift lenses on 35mm cameras. This can extend its apparent DOF.

Most of the reasons for preferring 35mm over larger formats also apply to preferring digital over 35mm.