1) that'll be fine. Just keep your bleach/fix containers separate from your developer containers, same as you would for B&W.
2) That depends whether you're doing one-shot (use small quantity, discard after one use), replenishing (use some quantity, discard small fraction of it & replace that with fresh), or extending the development time with successive batches (one big batch that slowly wears out and takes more development time). All three approaches are valid and the instructions should give you some idea as to how that chemistry is meant to be used.
Pro labs generally do replenishment as it's the most stable with large quantities being processed and most efficient use of chemistry. But you need to be developing a *lot* of film. The Fuji 5L kits for C41 and E6 both take the extended-development approach and provide a table of time extensions for successive batches through the life of the chems.