I too have recently printed my first 16x20 prints. I really dislike printing this large. Even though they are printed from 4x5 negatives and my entire workflow is dedicated to producing the sharpest negatives possible, they are just a little softer than I like to see. I also think the inverse square law applies to larger prints: the chances of everything going just right are inversely proportional to the square of the print size. 11x14 is my favorite size to print.