I print 20x24 in my 66"x71" darkroom with no issues at all. In fact the smallest I print is 11x14 due to what my market is. I use a Beseler 45MX with the baseboard converted to a magnetic easel which has pretty much replaced all my Saunders 4-blade easels. I use speed easels and the sheet metal covered baseboard with clear plexiglass strips cut to custom sizes with rare earth magnets taped on them. Most of the reason for this is how bad fiber based paper curls in my neck of the woods. I do up to 16x20 in trays that are stacked in a compact pull out shelf system and do fiber 20x24 in a Jobo 3063 drum on a motor base. I use a 80mm Apo-N Rodagon for my 6x6 and have three anti-newton glass carriers for all my formats including and oversized one for 4x5 that allows full frame.
The head is a Beseler 45S color head with a custom variable speed fan. All my other electronics are RH Designs including the Stop Clock Pro, Paper Flasher-II, Zonemaster-II and Process Master-II.
For a safelight system I use a Nova 5-star LED with 4 heads that is on a rheostat. Every time I change paper size, I check alignment with a laser alignment tool, it takes seconds to check and less than a minute to adjust.
I really don't think it is as hard as some here have made it out to be, it took me less than a month and two 10 packs of RC 20x24 paper to figure out that I could easily do gallery quality prints on fiber at this size. I am on assignment right now but once I am done, I will elaborate with more details if need be...