I have never made prints that big, although I have an enlarger that can do it (a horizontal 8X10 DeVere mural enlarger). Finding a good, working 8X10 enlarger can be a problem. One possibility, if you have experience with such things, is to modify an old 8X10 view camera or a view camera kit. A rigid support for such a thing could be quite a problem. Suspending it from the ceiling is a possibility, although that only helps.
Paper handling will be a problem. Trays are readily available for this size of paper, but sinks are more difficult. Some people build troughs of the appropriate size and seesaw the paper through the solutions during processing. In any case, diluting the developer beyond the usual recommendations will slow things down and make the paper easier to handle.