i used to print 16x20 often and loved seeing some of my hybrid prints
( made from camera-made + found + hand made negatives )
and often times i have a lab i work with print my work that big even today ... but
i also like, and almost favor smaller sizes (max 8x10, and even 4x5 reductions to 2x3 ) because
the form and line of an image really comes out more when it is compressed and i like miniatures + intimate prints.
in addition to small prints ( swimming in a large mat ) i also make hand stitched books
and find it to be much easier to make a book of 4x5 or 5x7 or 8x10 images than a book of 16x20 or 20x24 images.
have fun !