I don't see a reason it shouldn't. I use the older RF-602s (Canon version) with my RB67 ProS and YN-460 II flashes. Also have used it with a Yashica 35 P&S with PC-sync, OM40, OM10, AE-1, and a very old Schneider 360mm f/5.5 (Tele Xenon with really old shutter max 1/100th, but has pc-sync).

Use decent batteries, they have excellent range and are reliable unlike the older Chinese triggers (PT-04 etc).