It's fun! Try it out. What constitutes 'great' photography and print quality is highly individual, and when you go through a show at a museum where they show mural prints from 35mm by Salgado and more modest enlargements from large format negatives by photographers such as Andre Kertesz, and look at anything but resolution and grain, just marveling at the material and the stories the pictures tell, you realize how insignificant the negative size is in the grand scheme of things.
I think us photographers often fall ill with the disease of criticizing ourselves based on ultimate print quality, and my experience (as an observer at museums) is that only photographers care.
Mark Barendt, Beaverton, OR
"We do not see things the way they are. We see things the way we are." Ana´s Nin