I get "Wow, do they still make film?" and "Wow, you shoot film!?!), and everything in between.
The people that treat me with disdain get a brief (and polite) response from me...the folks that are intensely interested...we usually have a fun and interesting conversation. The best part is that I get clients because I shoot film, and I also get referrals from other professionals because I shoot film...that really makes me feel good, because then I know there are still folks out there who value it, besides us photographers.