I use the Zone system with large format and am very satisfied with the results. With roll film I used the concepts to determine an N exposure and development that prints on VC paper at grade 2 and use VC filters to get the result I visualized.

In his later years Ansel sometimes used a blad and had multiple backs labeled for normal, plus and minus development. In 35mm some prices are getting low enough that you could do the same thing with multiple bodies, may not be very practical though.