There are lots of anecdotes about his methodology by contemporaries. Some of the more interesting ones are by AA, who inevitably had to
contrast his own compartmentalized zone system to Weston's shrug of the shoulders voodoo approach, but really based upon experience and intuition. In the darkroom he was more of an alchemist than a chemist. Whatever worked. And there is some reason to believe that his habitual carelessness with pyro might have been what led to his Parkinson's disease. He never seemed obsessed with equipment. He couldn't afford to be.