If you are scanning from a print, you need to try to approximate it.
If you are scanning from a negative, you need to try for a result similar to what you might get in a print.
And if you are scanning from a slide, you need to try to make the result look like the slide.
The emphasis is on fidelity to the film based source. You need to avoid digital enhancements and digital manipulations - the results reasonably achievable in a darkroom should be your target.
And it is always okay to take steps to minimize the additions and distortions that a digital approach can add.