Andy Warhol apparently exhibited 8x10 inch prints in art galleries. He is said to have used a Minox subminiature camera for several years.
Anything is possible. And who knows maybe you have an idea that will break new ground. I am putting together a FrankenGraphic 4x5 camera from various parts and will be shooting one-of-a-kind originals on 4x5 paper. I think a lot of folks are doing this. Maybe we need a gallery show of our own. I've done the 11x14, 11x16 gallery route. I am ready for something new.