I have about 1 year of experience with TFX-2. My experience is limited to roll film. It is my favorite non-tanning developer. Of all of the films that I tried it with I felt it worked best with T-Max 100. It is an extremely flexible developer; depending on dilution and agitation you should be able to accomodate almost any contrast situation.
Most of the comments on FX-2 and TFX-2 in The Film Developing Cookbook" are true exept for stand developing. My experience was that it needed agitation at least once every 10 minutes to prevent streaking.
Although I have no experince with sheet film, I would expect it to be an good choice due to its resistance to oxidation.