Spots are totally unacceptable... That is why it is so important to handle film in the most pristine environment that one can have/afford. Spotting is such a frustrating and arduous task that the best thing is to never get dust and debris on your negatives in the first place. Having said that, dust is inevitable and your prints should be spotted.

One thing that I would recommend is to spend your time printing good negatives and eliminate the practice of "negative scanning" which increases the likelihood that negatives will become dirty or even scratched. Negatives IMHO negatives should be drying, in the glassine or being projected in a clean carrier and no place else.