And this is the rub... the tiniest mistakes will show up big-time in 35mm, where in larger formats you can get away with a little slop. I guess you need to ask yourself how you like to work. Would it be more fun to shoot MF handheld than 35mm on a tripod?
Everything is a tradeoff.

Quote Originally Posted by df cardwell
Will you be drum scanning the negs or enlarging them ? For the big prints you're looking at, you're at the edge of the capability of the normal best 35mm enlarging lenses, like an Apo Rodagon N and will probably need an Apo Rodagon G, optimize to the size you're working. And I'd suggest at least a Durst 1200 enlarger. This will even test your drum scanner. You're in the land of juggling chainsaws, Troy. Good luck.