Well, maybe, maybe not. As I am sure you are already aware there is no "magic bullet". However, that does not mean that we all don't try to find one (myself included).
i am also sure you have already been given the advice to stick with one combination until you really understand the results and how to control your materials. This includes the printing processes as well. However, you will probably (maybe or maybe not) reach a point were you are ready to try different options to create a different vision. When you reach that point just remember there are at least 10 different answers to one question answered by 5 "experts". Take it slow and test for yourself as the variables are huge and others can only share their experiences, altho valued they are not your experience.