No matter what the process, you still have to communicate a message, or a mystery to the viewer. you must make the viewer want to look again and again at the work and take time to contemplate its meaning. This takes vision, skill, knowledge and feeling on the part of the artist. People gravitate towards images that move them, nag at them and stick in their minds for a long time.
Digital will provide some of these images. The only probelm is you will have to sift through a lot of garbage to find them.