In MF, this limits you to using lenses with leaf shutters. No MF camera's focal plane shutter syncs with flash at a usefully high shutter speed. Do the thought experiment (ISO 100 film, 1/30 shutter speed, broad daylight) and you'll see why.
I respectfully disagree. I have never had many occasions to shoot a macro photo with higher than 1/30 using my SL66. With MF/LF, you are stopping down a fair bit, plus bellows factors, plus filter factors, plus slow film and its a non issue.