The short answer is NO. Connecting a 110VAC device to your 220VAC will cause damage. Using a converter ("step down transformer") won't work, because then you would be feeding 110VAC to the enlargers as well (unless you A- step the voltage back up or B- the enlargers need 110VAC). Remember than when you cut the voltage in half, the current will double - you might exceed the ratings on the timer. You'll be much better off with a timer designed for 220VAC than stringing together converters. The Gralab 500 is a digital timer, so the line frequency is irrelevent for timing. It is important depending on the power suppy design inside the timer, but this timer is rated for 50/60Hz.