I use an Epson 3200, and have been way less than impressed with the normal Epson defaults. I normally open Photoshop Elements and import from the scanner down near the TWAIN driver level, running the scanner in "Professional" mode, setting up levels via the histogram display and all (e.g., NOT using the auto-exposure mode). After that, resizing and a bit of USM usually produces reasonable results.

The top level interface I got from Epson they called "Smart Panel" and I fear its IQ is sadly lacking; it does cute stuff like using a gray scale in B&W text copy mode, etc.