This is how we used to print our own colour negative prints.
Using a glass neg carrier and the film taped, we would use 16x20" paper for a whole film, the only negative was the fact that invariably one had the odd over exposed or underexposed frame.
Basically we would do our normal print first, then guesstimate the difference for the under and over negatives. Generally we did it in three sheets, occasionally four sheets.
As it was standard practice to run 16x20" or 24x30" colour paper for test prints on our mural enlargements, these prints were considered collateral damage