For film shooters, the biggest hurdle, I think, when moving from 8x10" to 11x14" is the cost of the filmholders, but if you're shooting wetplate, that may not be so different. I would think that with wetplate the biggest issue would be the ability to pour a larger plate, but I'm not a wetplate photographer myself, so I would be interested to hear from the wetplate shooters on that.

My 1890's American Optical 11x14" field camera is an ultralight by 11x14" standards--about 15 lbs. I know someone with an 11x14" Wisner (Technical Field, if I remember correctly) that weighs 35 lbs.